Wu Liyu was born in Chiayi County, Taiwan in 1968. She graduated from the Department of Fine Arts, National Taiwan University of Arts in 1990, obtained her master's degree from the Department of Fine Arts, National Taiwan Normal University in 2004, and completed her Ph.D. in Art Creation and Theory Research at China Academy of Art in 2014. She has served as a lecturer at Hsuan Chuang University and Datong Community College.

She has held numerous solo exhibitions in Taiwan and abroad, with her most recent in Manhattan, New York. And has participated in over forty group exhibitions in art museums and galleries in New York, France, Canada, India, South Korea, Japan, China, as well as other regions. She has received awards in France, South Korea, and Taiwan, and her works are collected in Taiwan, mainland China, Singapore, Japan, and other regions.

Some of her recent significant exhibitions include: A solo exhibition at the Saphira & Ventura Gallery, New York, a group exhibition titled "Personal Narrative" at ODDO & CIE Gallery in France, Salon Paul Ricard Gallery in France, Air France Esplanade des Invalides group exhibition in France, Caroun Art Gallery international exhibition in Canada, "Personal Narratives" at Roerich Art Gallery & Museum in Naggar, Kullu Manali, Himachal Pradesh, India, "Black and White" international art exhibition at Roerich Gallery in India, International Art Exhibition in Ulaanbaatar, Mongolia, "Grassland Connected to the World" First International Art Invitation Exhibition in Baotou, India IRMT GALLERY International Art Exhibition, International Grand Square & North Gate Art-International Contemporary Art Exhibition in Mongolia, 2017 Taichung Art Expo, 2017 Tainan Art Expo, 2018 Taipei Art Expo, 2019 Tainan Art Expo, "Whimsy" International Exhibition by Baijiahu International Exhibition Company, "Whimsy" International Exhibition at Nanjing Yiyi Art Space, "Collective Inner Desires" International Artist Group Exhibition at S7 Art Museum, 2019 Guangzhou Art Expo, 2019 Shanghai Art Expo, 2019 Taipei Art Expo, 2020 Taipei Art Expo.

Wu Liyu studio is located in Taipei, Taiwan.